One bullet type that should get serious consideration for defensive use is the Barnes all-copper hollowpoint bullet. This type is one that's used by the folks at Cor-Bon and they call it their DPX bullet. For their 9mm Luger standard-pressure load (as opposed to the high-pressure "+P" load), they use a 95gr. bullet and rate the load at 1300FPS from a 3=1/2" test barrel. This load has gotten some seriously good reports when tested on animal cadavers. I use Cor-Bon DPX loads in my LCP (.380 ACP) and my Glock 19 (9mm).
Click on this link for Cor-Bon's web page on their DPX loads.